Retinopathy of prematurity (ROP) is the most common cause of childhood blindness in developed countries and in Puerto Rico. Neonates born before 3o weeks of gestational age or with low birth weight have higher risk for developing ROP. In preterm infants the peripheral retina is not fully mature and may develop abnormal vasculature after premature birth. Without treatment, abnormal retinal development may lead to retinal detachment and blindness.
Other pediatric retinal conditions such as persistent hyperplastic primary vitreous (PHPV), Norrie's disease, familial exudative vitreoretinopathy (FEVR), retinoschisis, may have features similar to ROP. A complete ophthalmologic exam including photography, optical coherence tomography (OCT), and ultrasound may be necessary for diagnosis.